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br Introduction br Literature review and hypothesis developm
2020-10-31

Introduction Literature review and smad pathway development CPA exam performance-related research has been of interest to academics for the past few decades. These studies have ranged from investigating the impact of the 150-hour requirement on pass rates (Allen & Woodland, 2006) to examining
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br Introduction br Conclusion br Acknowledgments and Funding
2020-10-31

Introduction Conclusion Acknowledgments and Funding Introduction Reversible protein phosphorylation is an important post-translational modification of proteins regulating many processes in the cell. Approximately one third of the cellular proteome is phosphorylated, and several sites are
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br Steroid biosynthesis br Steroid hormone metabolism in bre
2020-10-31

Steroid biosynthesis Steroid hormone metabolism in breast cancer Conclusion Steroid hormones elicit their biological actions primarily by binding to steroid receptors such as the ER, AR, PR and GR. Although classical breast cancer diagnostic panels assess the expression of the ER and PR, as
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Exogenous administration of POCs could
2020-10-31

Exogenous administration of POCs could theoretically inhibit breastfeeding [69]; however, the evidence in this review does not generally support a negative impact on breastfeeding outcomes. Studies examining the Celecoxib of POCs among postpartum women overall demonstrated no adverse effects on meas
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The defining molecular feature of Ewing sarcoma is the chara
2020-10-31

The defining molecular feature of Ewing sarcoma is the characteristic EWSR1/ETS fusion protein, most commonly involving EWSR1 and FLI1 (Delattre et al., 1992, May et al., 1993). EWS–FLI1 causes global changes in gene expression both by directly regulating gene expression and by causing changes in ch
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br Structure of USP Schematic representation of the USP
2020-10-31

Structure of USP7 Schematic representation of the USP7 domain architecture is shown in Fig. 3B. USP7 is a 135 kDa protein that consists of seven domains, including the N-terminal TRAF-like (Tumor necrosis factor Receptor–Associated Factor) domain, followed by the catalytic core domain and the fiv
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Introduction With an annual world production of around milli
2020-10-31

Introduction With an annual world production of around 750 million tons, wheat is grown on more agricultural area than any other food crop and is the main source of plant protein in human nutrition [1,2]. Wheat is composed of 8–15% protein, from which 85–90% is gluten [3]. The unique viscoelastic a
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The host virus coexistence is completely dependent
2020-10-31

The host-virus coexistence is completely dependent on the balance between a strong immune response inhibiting virus replication and immune evasion and survival of the virus with periodic shedding to enable transmission to new hosts. In the process of ensuring this balance, the virus manipulates 7TM
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br Materials and methods br Results br Discussion Innate
2020-10-31

Materials and methods Results Discussion Innate immunity plays an essential role in the control and elimination of bacterial infection through production of inflammatory cytokines (Liu et al., 2015). Production of inflammatory cytokines requires the recognition of bacterial pathogen-associa
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Psalmotoxin 1 HCV has evolved mechanisms to
2020-10-31

HCV has evolved mechanisms to evade humoral immune responses including high functional flexibility and variability of immunogenic portions of its envelope proteins. The highest sequence variability occurs in the first 27 Psalmotoxin 1 of the N-terminus of E2, which is referred to as the hypervariabl
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Our observation that FAK is downregulated in
2020-10-31

Our observation that FAK is downregulated in vascular smooth muscle phenethyl on fibrillar collagen confirms observations reported for other cell types [14]. However, unlike the results reported previously [14], our work suggests that matrix rigidity per se does not determine FAK downregulation. Thi
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Ethyl naphthoates a h were successfully
2020-10-30

Ethyl 1-naphthoates (10a–h) were successfully reduced to 1-naphthylmethanols (12a–h) by using LiAlH4 with 8–87% yields. Then PCC was used to convert the alcohols into the corresponding 4-alkyl-1-naphthaldehyde derivatives (13a–h) with relatively higher yields (58–90%) as represented in Scheme 2. The
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ClC is a member of the
2020-10-30

ClC-3 is a member of the voltage-gated chloride channel superfamily and has many roles in cell proliferation, apoptosis, Eeyarestatin I progression and so on (Dai et al., 2005). A growing number of studies showed that ClC-3 encoded a volume-regulated Cl− channel (ICl,Vol) in heart, that could contri
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These findings further extend our knowledge of how P and
2020-10-30

These findings further extend our knowledge of how P4 and/or E2 can mediate anxiety and fear responses. Female rats in behavioral estrous and ovx rats administered systemic P4 and/or E2 demonstrated significantly less anxiety in the open field and/or elevated plus maze, compared to diestrous rats, a
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The activity of cysteine endopeptidases involved in the germ
2020-10-30

The activity of cysteine endopeptidases involved in the germination of caryopses is generally regulated at two levels: the hormonal induction of synthesis by gibberellins (Drzymała et al., 2008) and a putative regulation of activity by phytocystatines (Kiyosaki et al., 2007, Martinez et al., 2009),
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